Recovery Peptides Anti-aging Growth Factors Under research

MGF

Also known as: Mechano Growth Factor, IGF-1Ec

MGF (Mechano Growth Factor), also known as IGF-1Ec, is a splice variant of insulin-like growth factor-1 (IGF-1). It is produced locally in skeletal muscle in response to damage or mechanical stress (such as resistance training). It is crucial for tissue repair, stimulating the proliferation of satellite cells (muscle stem cells) before they differentiate into mature muscle fibers.

Mechanism of action

Transiently expressed following muscle damage from mechanical stress.
Stimulates activation and proliferation of myogenic stem cells (satellite cells).
Prevents apoptosis (programmed cell death) in damaged tissue.
Acts through IGF-1 independent receptors to promote repair before other IGF-1 isoforms stimulate differentiation.

Uses & indications

Muscle hypertrophy: Extreme acceleration of localized muscle growth.
Injury recovery: Local injection into torn muscles or tendons.
Muscle anti-aging: Prevention of sarcopenia.

Effects

Massive targeted muscle growth, rapid repair of damaged muscle tissue. It has no significant systemic effect due to its extremely short half-life (minutes).

Considerations & contraindications

Must be injected directly into the trained or injured muscle immediately after exercise.
Half-life of only 5-7 minutes in the bloodstream.
Research use only, banned in sports competitions.

Regulatory approval

Research substance. Not approved by regulatory agencies.

Dosage

Typically 200mcg injected intramuscularly (divided bilaterally in the target muscle) immediately post-training.

Storage

Lyophilized at -20°C. Reconstituted at 4°C and use within 7 days due to instability.

Technical data

Regulatory status Under research

Molecular weight 2888.16 Da

Half-life 5 - 7 minutos

Administration routes Intramuscular localizada (bilateral)

MGF